According to The Kobeissi Letter, Berkshire Hathaway has achieved a staggering 5,502,284% return since 1964, vastly outperforming the S&P 500's 39,054% return over the same period. This equates to a compounded annual gain of 19.9% for Berkshire compared to 10.4% for the S&P 500, marking it as one of the most remarkable long-term investment records in history.